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Metabolic & Cardiometabolic

adolescent anabolic-steroid use stunts adult height via growth-plate closure

In plain terms: Can teenage anabolic-steroid use permanently stunt height?

Leans support Metabolic & Cardiometabolic
RefutedContestedStrong support
consensus score 0.55

Yes — androgens aromatize to estrogen, which prematurely fuses the growth plates; this is well-established endocrinology (high-dose testosterone is even used clinically to close plates in very tall teens), so steroid use before growth finishes can permanently limit height.

📅 Last reviewed: 2026-07-14

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: Population patterns (Observational)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

11 support 0 contradict 0 tested null 1 mixed · 12 sources, 11 independent groups

The evidence (12)

SourceGradeStanceQualityFinding
Witbreuk M et al
2013 · study_type: mechanism
mechanism supports low Systematic review on slipped capital femoral epiphysis describes how activation of the gonadal axis and the resulting GH-IGF-1 axis surge drive pubertal growth-plate (physis) weakening and eventual cessation at the end of puberty.
Wit JM.
2021 · study_type: mechanism
mechanism supports low Review of skeletal maturation manipulation notes that blocking conversion of androgens to estrogens (via aromatase inhibitors) delays epiphyseal fusion and can increase adult height, implying the reverse: androgen exposure (via aromatizatio
Thodberg HH et al
2026 · study_type: RCT
observational supports low Case-control trial of oxandrolone vs placebo in 90 boys with Klinefelter syndrome showed androgen treatment accelerated bone age advancement (0.24, 0.77, 1.24, 1.43 years at 6/12/18/24 months), detectable by 6 months. Bone age advancement i
Vanderschueren
2005 · Horm Res
mechanism supports moderate Androgens and their aromatized estrogens drive skeletal maturation and epiphyseal fusion during puberty.
Matsuo
2006 · Nihon Rinsho
mechanism supports moderate Excessive prepubertal androgens advance bone maturation and cause premature epiphyseal closure and short stature.
Juul
2001 · Growth Horm IGF Res
mechanism supports moderate High sex-steroid exposure, via aromatization to estrogen, drives epiphyseal fusion and terminates linear growth.
Savage
2002 · Horm Res
observational supports moderate Chronic androgen excess causes early epiphyseal fusion and adult short stature in affected children.
Mohamed S et al
2019 · study_type: meta-analysis
meta-analysis mixed high [SCOPE: therapeutic low-dose oxandrolone in Turner-syndrome girls, NOT illicit supraphysiologic AAS abuse in adolescent boys] Cochrane meta-analysis of 6 RCTs (498 adolescent girls with Turner syndrome) found oxandrolone added to growth hor
Jaruratanasirikul
2011 · J Med Assoc Thai
observational supports moderate Untreated early sex-steroid-driven puberty results in short adult stature from premature growth-plate closure.
Smith
1996 · Baillieres Clin Endocrinol Metab
mechanism supports moderate Estrogen, largely from aromatized androgen, is the principal driver initiating and completing epiphyseal closure.
Hoffman
2009 · J Strength Cond Res
observational supports low An NSCA position stand notes androgen use in adolescents risks premature epiphyseal closure and compromised growth.
Meazza
2017 · Ital J Pediatr
mechanism supports low High-dose testosterone is used clinically in tall adolescents to induce epiphyseal fusion and reduce final height.

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