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Metabolic & Cardiometabolic

adolescent anabolic-steroid use decreases adult height via growth-plate closure

In plain terms: Can teenage anabolic-steroid use permanently stunt height?

Leans support Metabolic & Cardiometabolic
RefutedContestedStrong support
consensus score 0.54

Yes — androgens aromatize to estrogen, which prematurely fuses the growth plates; this is well-established endocrinology (high-dose testosterone is even used clinically to close plates in very tall teens), so steroid use before growth finishes can permanently limit height.

📅 Last reviewed: 2026-07-14 ⓘ

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: Population patterns (Observational)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

10 support 0 contradict 0 tested null 1 mixed · 11 sources, 10 independent groups

What the evidence shows

The endocrinology is well established: androgens aromatise to oestrogen, which advances skeletal maturation and prematurely fuses the growth plates, and excessive prepubertal androgen exposure causes early epiphyseal closure and short stature. Direct evidence in adolescents using steroids recreationally is thin, resting on mechanism and on clinical androgen treatment in other conditions.

The evidence (12)

SourceGradeStanceQualityFinding
Witbreuk M, van Kemenade FJ, van der Sluijs JA, Jansma EP, Rotteveel J, van Royen BJ
2013 · Journal of children's orthopaedics
mechanism supports low Systematic review on slipped capital femoral epiphysis describes how activation of the gonadal axis and the resulting GH-IGF-1 axis surge drive pubertal growth-plate (physis) weakening and eventual cessation at the end of puberty.
Wit JM
2021 · Frontiers in endocrinology
mechanism supports low Second, the combination of a GnRHa with an anabolic steroid was investigated in two studies with an apparently positive effect on AH compared with matched controls ( 34 , 35 ) (LoE 3), but since then no more data have been presented.
Thodberg HH, Aksglaede L, Juul A, Davis SM, Ross J
2026 · Scientific reports
observational supports low Case-control trial of oxandrolone vs placebo in 90 boys with Klinefelter syndrome showed androgen treatment accelerated bone age advancement (0.24, 0.77, 1.24, 1.43 years at 6/12/18/24 months), detectable by 6 months. Bone age advancement i
Vanderschueren D, Vandenput L, Boonen S
2005 · Horm Res
mechanism supports moderate Androgens and their aromatized estrogens drive skeletal maturation and epiphyseal fusion during puberty.
Matsuo K, Fujieda K
2006 · Nihon Rinsho
mechanism supports moderate Excessive prepubertal androgens advance bone maturation and cause premature epiphyseal closure and short stature.
Juul A
2001 · Growth Horm IGF Res
mechanism supports moderate High sex-steroid exposure, via aromatization to estrogen, drives epiphyseal fusion and terminates linear growth.
Savage MO, Scommegna S, Carroll PV, Ho JT, Monson JP, Besser GM, Grossman AB
2002 · Horm Res
observational supports moderate Chronic androgen excess causes early epiphyseal fusion and adult short stature in affected children.
Mohamed S, Alkofide H, Adi YA, Amer YS, AlFaleh K
2019 · The Cochrane database of systematic reviews
meta-analysis mixed high [SCOPE: therapeutic low-dose oxandrolone in Turner-syndrome girls, NOT illicit supraphysiologic AAS abuse in adolescent boys] Cochrane meta-analysis of 6 RCTs (498 adolescent girls with Turner syndrome) found oxandrolone added to growth hor
Jaruratanasirikul S, Thaiwong M
2011 · J Med Assoc Thai
observational supports moderate Untreated early sex-steroid-driven puberty results in short adult stature from premature growth-plate closure.
Smith EP, Korach KS
1996 · Baillieres Clin Endocrinol Metab
mechanism supports moderate Estrogen, largely from aromatized androgen, is the principal driver initiating and completing epiphyseal closure.
Hoffman JR, Kraemer WJ, Bhasin S, Storer T, Ratamess NA, Haff GG, Willoughby DS, Rogol AD
2009 · J Strength Cond Res
observational supports low An NSCA position stand notes androgen use in adolescents risks premature epiphyseal closure and compromised growth.
Meazza C, Gertosio C, Giacchero R, Pagani S, Bozzola M
2017 · Ital J Pediatr
mechanism supports low High-dose testosterone is used clinically in tall adolescents to induce epiphyseal fusion and reduce final height.

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