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Diets

cruciferous vegetables decreases cancer risk

In plain terms: Does eating cruciferous vegetables lower cancer risk?

Strong support Diets 🔬 Includes disconfirming
RefutedContestedStrong support
consensus score 0.62

Yes as an observational association (~10-20% lower risk for several cancers), but it is correlational, not proof that the vegetables themselves cause the reduction.

📅 Last reviewed: 2026-07-14

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: All trials, pooled (Meta-analysis)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

9 support 1 contradict 0 tested null 4 mixed · 14 sources, 10 independent groups

The evidence (14)

SourceGradeStanceQualityFinding
Yu
2022 · Front Nutr
meta-analysis contradicts moderate Meta-analysis of cohort studies found only weak/inconsistent association between cruciferous intake and bladder cancer risk.
Li
2024 · Gynecol Obstet Invest
meta-analysis supports moderate Dose-response meta-analysis found cruciferous vegetable consumption associated with lower ovarian cancer risk.
Silva IAD et al
2025 · study_type: observational
observational mixed low Prostate cancer, Brazilian case-control (125 cases/250 controls): cruciferous vegetable intake reduced risk by 22% per gram/day, OR=0.978 (95% CI 0.96-1.00), borderline p=0.052.
Ren
2024 · Crit Rev Food Sci Nutr
meta-analysis supports moderate Meta-analysis of 89 studies found highest cruciferous intake associated with ~19% lower gastrointestinal cancer risk with a dose-response.
Tabatabaei
2025 · J Cancer Prevention
meta-analysis supports moderate In pooled prospective cohorts, cruciferous vegetable intake was associated with ~18% lower lung cancer risk (RR 0.82), though without a clear non-linear dose-response.
Wu Q et al
2026 · study_type: observational
observational supports low Bladder cancer (NMIBC) late recurrence, case-control (n=264): low cruciferous intake (<1 serving/week) independently associated with increased recurrence risk, aOR=2.41 (95% CI 1.42-4.10), dose-response trend p<0.05.
Guo
2024 · J Food Sci
meta-analysis supports moderate Umbrella review of 22 meta-analyses found cruciferous vegetable intake associated with reduced risk across multiple cancers.
Long
2023 · Urologia Internationalis
meta-analysis mixed low The association between cruciferous vegetable intake and prostate cancer risk was weak and inconsistent, remaining contentious.
Zhang D et al
2026 · study_type: meta-analysis
meta-analysis supports low Bladder cancer, umbrella review of 84 meta-analyses: cruciferous vegetable intake ≥412.5 g/week associated with reduced risk, rated low-to-moderate certainty by GRADE overall.
Tang L et al
2025 · study_type: observational
observational mixed moderate Breast cancer survival, Pathways prospective cohort (n=3,656): cruciferous intake inversely associated with total invasive events in age-adjusted models (HR 0.86, 95% CI 0.77-0.97 per serving) but null in multivariable models (HR 0.91, 95%
Zheng
2025 · Nutrition Reviews
meta-analysis mixed moderate A dose-response meta-analysis found cruciferous vegetable intake inversely associated with several cancers but with differential, non-uniform effects across cancer types.
Lai
2025 · BMC Gastroenterology
meta-analysis supports moderate A dose-response meta-analysis found higher cruciferous vegetable intake associated with reduced colon cancer risk, attributed to glucosinolate-derived isothiocyanates.
Zhang
2024 · Eur J Nutr
meta-analysis supports moderate Updated meta-analysis found cruciferous vegetable intake associated with reduced pancreatic cancer risk.
Baladia
2024 · Nutrients
meta-analysis supports moderate A meta-analysis of observational studies found broccoli consumption inversely associated with cancer risk, though results were not fully consistent across studies.

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