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erythritol causes gastrointestinal symptoms

Contested Sweeteners πŸ”¬ Includes disconfirming

Part of: β€’ erythritol

RefutedContestedStrong support
consensus score -0.10

πŸ“… Last reviewed: 2026-07-15 β“˜

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: Human trials (RCT / n-of-1)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

1 support 3 contradict 1 tested null 1 mixed Β· 6 sources, 4 independent groups

What the evidence shows

Contrary to the 'sugar alcohols wreck your gut' reputation, erythritol is the best-tolerated polyol: because ~90% is absorbed in the small intestine (unlike xylitol/sorbitol, which ferment in the colon), it causes far less gas, bloating and osmotic diarrhea.

The evidence (6)

SourceGradeStanceQualityFinding
EFSA Panel on Food Additives and Flavourings (FAF) et al
2023 Β· study_type: observational
observational supports high EFSA re-evaluation synthesizing human interventional studies; erythritol dose-dependently causes diarrhea, with NOAEL of 0.5 g/kg bw identified and an ADI set at that level to protect against laxative effects; high-intake consumers (childre
Teysseire et al.
2024 Β· Nutrients
observational tested-null low Narrative review: very high erythritol doses can cause some GI discomfort, but tolerance generally good.
Mazi & Stanhope
2023 Β· Nutrients
observational mixed low Review: erythritol well-tolerated; GI effects far lower than xylitol/sorbitol at comparable doses.
de Cock
2018 Β· Adv Dent Res
observational contradicts moderate Erythritol is metabolized differently from other polyols β€” absorbed and renally excreted, so low fermentation and good GI tolerance.
Bordier V et al
2023 Β· study_type: RCT
RCT contradicts low RCT, 42 obese adults, 36g erythritol or 24g xylitol daily x5 weeks vs no-treatment control; gastrointestinal tolerance was good overall with only a few diarrhoea-related symptoms reported.
Wolnerhanssen et al.
2020 Β· Crit Rev Food Sci Nutr
observational contradicts moderate Metabolic review: erythritol largely absorbed in small intestine, markedly better GI tolerance than other polyols (less laxative/gas).

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