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Supplements · Metabolic & Cardiometabolic

Does psyllium fibre lower "bad" cholesterol?

The claim, precisely: psyllium decreases LDL cholesterol

Strong support Supplements
RefutedContestedStrong support
consensus score 1.00

Yes — well-established across many trials, and gentle on sensitive guts.

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: All trials, pooled (Meta-analysis)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

5 support 0 contradict 0 tested null 0 mixed · 4 sources, 4 independent groups

What the evidence shows

Psyllium lowers LDL, non-HDL and ApoB (~10 g/d), with FDA-claim precedent in baked/cereal matrices — and it is low-FODMAP / IBS-friendly.

The evidence (5)

SourceGradeStanceQualityFinding
Wei
2009 · Eur J Clin Nutr
meta-analysis supports moderate [FT-verified] Wei2009 21RCTs n=1717 LDL -0.278 mmol/L; significant dose-response 3-20g/d
Jovanovski E, et al.
2018 · Am J Clin Nutr
meta-analysis supports high [FT-verified] Jovanovski2018 28RCTs n=1924 LDL MD -0.33 mmol/L (CI -0.38,-0.27); apoB -0.05; GRADE mod-high
Jovanovski E, et al.
2018 · Am J Clin Nutr
meta-analysis supports high Significant reduction in LDL, non-HDL, ApoB at ~10 g/d
Schoeneck 2021
2021 · Nutr Metab Cardiovasc Dis
meta-analysis supports high Umbrella review: viscous fibers incl psyllium consistently lower LDL-C with strongest evidence
Juhasz
2023 · Am J Clin Nutr
meta-analysis supports high Network MA in T2D: soluble fibers incl psyllium reduce LDL/lipids

Educational only, not medical advice. Grades and scores reflect published evidence weighted by study design and quality; see the methodology.